Peer-reviewed articles by
Dr Rajesh Shah

Protection From SARS-CoV-2 Infection
With an Oral Nosode (BiosimCovex): A
Randomized, Double-Blind,
Placebo-Controlled, Phase III Study

Protection From SARS-CoV-2 Infection

This study evaluated an oral preventive medicine, BiosimCovex, to determine if it could safely reduce the incidence of COVID-19 infections. Results showed that it was safe, reduced infections, and increased antibody levels. Thus, served as an oral preventive measure for COVID-19.

Conclusion:

  • It gave up to 72% protection against COVID-19 infection
  • Observed a statistically significant antibody-positive rate
  • Safe and oral dose option for the prevention of infection

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Protection From SARS-CoV-2 Infection

Peer-review articles 02

Evaluating the anti-bacterial activities of potentized medicines on the clinical isolates from the urine samples

Evaluating the anti-bacterial activities

Homeopathic medicines, known as nosodes, were tested against bacteria from urinary infections in the laboratory. Many nosodes demonstrated antibacterial effects, and drugs were able to slow or halt the growth of certain bacteria. Surprisingly, their effect was comparable to that of a commonly used antibiotic, suggesting a possible role in treating infections due to their antimicrobial action.

Conclusion:

  • Efficacy ranging from 94% to 60% against different bacterial strains was demonstrated.
  • This study unveils the therapeutic potential of homeopathic medicines against antibiotic-resistant bacterial strains.

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Evaluating the anti-bacterial activities

Peer-review articles 03

Evaluating anticancer potentials of potentized preparations in an in-vivo xenograft model

Evaluating anticancer potentials

New homeopathy preparations were tested in mice with human lung cancer tumors. Two medicines, namely, HIV 30c and Cancer 30c, given orally, significantly slowed tumor growth and improved survival compared to untreated mice.

Conclusion:

  • Results are suggestive of tumor regression.
  • The results suggest these medicines might have anticancer effects and are safe to administer.

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Evaluating anticancer potentials

Peer-review articles 04

Acute, subacute, repeated dose toxicity and safety studies of BiosimCovex (COVID-19 Nosode) in an animal model

Acute, subacute,repeated dose toxicity

This study tested whether a homeopathic COVID-19 nosode called BiosimCovex is safe in animals. Researchers gave mice, rats, and rabbits different doses, such as one-time and repeated doses, and watched for any toxic effects. They found no significant toxic effects, suggesting the nosode was safe at the tested doses in this animal model.

Conclusion:

  • No toxicity was documented using acute, subacute, and repeated dose studies
  • Proven safe to administer orally

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Acute, subacute,repeated dose toxicity

Peer-review articles 05

A Randomized, Placebo-controlled Homeopathic Drug-proving of SARS-CoV-2 nosode (BiosimCovex) in healthy volunteers

Randomized, Placebo-controlled Homeopathic Drug

This study administered either the homeopathic COVID-19 nosode BiosimCovex or a placebo to healthy volunteers to assess the reported symptoms and safety. More symptoms were reported by those taking BiosimCovex than by those taking the placebo, and no serious side effects were observed. The results suggest the nosode was safe to use and produced characteristic symptom patterns in volunteers.

Conclusion:

  • The BiosimCovex nosode has demonstrated its safety and specific symptoms in a homeopathic drug proving
  • Supporting BiosimCovex’s inclusion in the homeopathic literature

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Randomized, Placebo-controlled Homeopathic Drug

Peer-review articles 06

The Challenge of Non-Reproducibility of Old Homoeopathic Drugs and the Need for their Standardisation and Re-Proving

Non-Reproducibility of Old Homoeopathic Drugs

This review highlights that many old homeopathic medicines lack clear information about their source and preparation, making them hard to reproduce reliably. It describes a need for fresh provings, and better-quality control to improve safety and consistency in homeopathic practice

Conclusions:

  • Most traditional homeopathic drugs are hard to reproduce due to vague source/preparation records
  • The authors call for modern standardisation, fresh provings, and better tracking to ensure quality and reliability

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Non-Reproducibility of Old Homoeopathic Drugs

Peer-review articles 07

A Randomised, Double-Blind Placebo-Controlled, Multi-Centric Clinical Trial of Ultra-Diluted Mycobacterium tuberculosis Nosode (Emtact 30c) in the Management of Recurrent Upper and Lower Respiratory Tract Affections

A Randomised, Double-Blind Placebo-Controlled

This study evaluated the Mycobacterium Tuberculosis nosode (Emtact), made from tuberculosis bacteria, to see if it is effective in people with frequent colds, coughs, and breathing problems. In a six-month trial, people taking Emtact had reduced symptoms like blocked nose, poor sleep, and tiredness compared to those on a placebo, with a few health markers improved.

Conclusions:

  • The results indicated a significant reduction in symptoms like nasal blockage, sneezing, and watery nasal discharge
  • The severity of repeated respiratory infections was lowered
  • Emtact may be used as a safe and efficacious alternative to treat URT and LRT affections

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A Randomised, Double-Blind Placebo-Controlled

Peer-review articles 08

Safety and Evaluation of the Immune Response of Coronavirus Nosode (BiosimCovex) in Healthy Volunteers: A Preliminary Study Extending the Homeopathic Pathogenetic Trial

Safety and Evaluation of the Immune Response of Coronavirus Nosode

This Phase I study, conducted in the early stages, administered a homeopathic COVID-19 nosode called BiosimCovex orally to 10 healthy volunteers for 3 days to assess its safety and potential to trigger immune responses. No serious side effects were seen, and some immune markers (like IL-6 and CD4 cells) changed over time, suggesting possible biological effects worth further study

Conclusions:

  • BiosimCovex appeared safe with no serious adverse effects in the small group tested
  • Changes in immune markers suggest possible signals that should be explored in larger studies.

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Safety and Evaluation of the Immune Response of Coronavirus Nosode

Peer-review articles 09

Proposed Standards and Regulatory Mechanisms for New Homeopathic Drug Development

Standards and Regulatory Mechanisms

This review describes that the new homeopathic medicines development mechanism lacks clear, standardized rules, especially in India. The authors propose practical steps for identifying, testing, regulating, and approving new homeopathic drugs to enhance transparency and consistency in the process

Conclusions:

  • There is an urgent need for clear guidelines and regulatory pathways for new homeopathic drug development
  • The authors propose achievable standards and an independent regulatory body to support research and market approval

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Standards and Regulatory Mechanisms

Peer-review articles 10

Randomized Double-Blind, Placebo-Controlled Feasibility Study, Evaluating the Efficacy of Homeopathic Medicines in the Prevention of COVID-19 in a Quarantined Population

Randomized Double-Blind, Placebo-Controlled Feasibility Study

This feasibility study tested homeopathic medicines (like Bryonia alba 30c and a coronavirus nosode/ BiosimCovex 30c) against a placebo in quarantined individuals after exposure to COVID-19. The groups taking Bryonia alba or BiosimCovex showed a trend toward fewer COVID-19 cases and shorter illness than the placebo

Conclusions:

  • Homeopathic nosode BiosimCovex and Bryonia alba 30c showed signals of potentially lowering COVID-19 incidence and disease prevention
  • Shortening the course of disease symptomatology in a COVID-19-exposed population

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Randomized Double-Blind, Placebo-Controlled Feasibility Study

Peer-review articles 11

Preparation and Standardization of Nosodes Sourced from Klebsiella Pneumoniae, Salmonella Typhi, Neisseria Gonorrhoeae and Candida Albicans Strains

Preparation and Standardization of Nosodes

This study describes how scientists systematically made and standardized Klebsiella Pneumoniae, Salmonella Typhi, Neisseria Gonorrhoeae and Candida Albicans nosodes from bacteria and fungi that cause infections. They used modern methods to prepare these nosodes to replace or remake old versions with unclear sources. The work supports further research and quality control in homeopathic nosode production

Conclusions:

  • The researchers established a clear process to prepare and standardize nosodes from specific infectious organisms
  • This systematic approach improves reproducibility and sets the stage for future research on their effects

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Preparation and Standardization of Nosodes

Peer-review articles 12

An open-label, exploratory documentation of proving-symptoms of CVN01 (Coronavirus nosode from the clinical sample) in healthy volunteers

An open-label, exploratory documentation of proving-symptoms

This study is an open-label trial to evaluate the safety and provoking symptoms of Coronavirus nosode. The symptoms reported by volunteers were mild to severe but reversible and matched the symptoms produced by the viral infection. There were no serious/fatal adverse events during the study. The basic biochemistry and Liver Function tests were not affected by the Nosode.

Conclusions:

  • A new nosode developed during a pandemic condition produced certain symptoms in the homeopathic pathogenetic trial
  • The safe use of the nosode is documented

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An open-label, exploratory documentation of proving-symptoms

Peer-review articles 13

In-Vitro Evaluation of Antimicrobial Activities of Escherichia coli, Klebsiella pneumoniae, Salmonella typhi, Neisseria gonorrhoeae, and Candida albicans Nosodes

Antimicrobial action

We studied homeopathic nosodes (E. coli, K. pneumoniae, S. typhi, N. gonorrhoeae, C. albicans) in an in vitro model to determine if they could inhibit the growth of these microbes using a minimum inhibitory concentration (MIC) assay. Escherichia coliKlebsiella pneumoniaeSalmonella typhiNeisseria gonorrhoeae, and Candida albicans nosodes showed growth inhibition against the corresponding microorganisms and others.

Conclusions:

  • C. albicansN. gonorrhoeae, and the positive control amphotericin B showed inhibition of the growth of the C. albicans species
  • K. pneumoniae and E. coli showed inhibition of the growth of K. pneumoniae; interestingly, this effect was not seen with ceftriaxone, ofloxacin, and amoxicillin antibiotics
  • Several nosodes showed antibacterial or antifungal activity in vitro against the tested organisms

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Antimicrobial action

Peer-review articles 14

Preparation of Coronavirus nosodes sourced from a clinical sample of SARS-Cov-2 positive patient, inactivated strain, and spike glycoprotein
Coronavirus Nosode article

BiosimCovex preparation (1)

In May 2020, at the beginning of the COVID-19 pandemic,  scientists prepared three types of homeopathic coronavirus nosodes from (1) a clinical sample, (2) a heat-inactivated virus strain, and (3) the spike protein. They checked that the materials were free of detectable virus RNA at higher dilutions, following homeopathic preparation methods, to make them safe for future research

Conclusions:

  • Three SARS-CoV-2-derived nosodes were successfully prepared and standardized under biosafety conditions
  • These nosode preparations showed no detectable RNA at potentized levels, thus rendering them safe for human consumption

Link:

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BiosimCovex preparation (1)

Peer-review articles 15

Preparation and Standardization of Escherichia coli Nosodes Sourced from Select E. coli Strains

E coli pren (1)

This study describes how scientists cultured E. coli bacteria from three laboratory strains and used them to produce and standardize homeopathic nosodes. They checked the source purity and ensured no live bacteria or DNA remained in the final preparations. The source and characterization parameters are well documented.

Conclusions:

  • Multiple E. coli-derived nosodes were successfully prepared and standardized using rigorous culturing and potentization methods
  • Safety testing showed the absence of contamination or detectable DNA in potentized nosodes, supporting further efficacy studies

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E coli pren (1)

Peer-review articles 16

BIOPHYSICAL TECHNIQUES REVEALED INSIGHT OF POTENTIZED SOLVENT OF ETHANOL-WATER INTERFACE

Biophysics (1)

This study used UV-visible, fluorescence, and Raman spectroscopy to examine homeopathic preparations (potentized ethanol-water mixtures with sulfur). The potentized samples showed changes in light absorption, fluorescence, and molecular interactions compared to controls, suggesting altered physicochemical properties due to potentization

Conclusions:

  • Potentized ethanol–water samples showed clear changes in UV/fluorescence and Raman signals, indicating altered molecular behavior
  • Raman spectroscopy indicated a significant change in electronic configuration as well as the intermolecular interaction in the liquid phase in potentized preparations
  • Based on the study results, scientists hypothesize that some structural changes may occur in potentized samples.

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Biophysics (1)

Peer-review articles 17

The Preparation and standardization of Human papillomavirus (HPV) (Genotype 6) Nosode

HPV nosode

Well-identified and characterized source material for HPV nosode preparation was identified by Dr Rajesh Shah and processed according to biosafety guidelines. Nosode underwent testing to document its HPV genotype 6, and potencies are free from detectable viral DNA, providing a safe and standardized product for use

Conclusions:

  • A nosode from HPV genotype 6 was successfully prepared and standardized with confirmed sterility and no detectable viral DNA at potentized levels
  • The aim is to use this standardized nosode in future research to explore potential therapeutic or preventive effects against HPV-related conditions

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HPV nosode

Peer-review articles 18

Evaluating the anticancer effects of high-dilution preparations of carcinogens such as HIV virus, Hepatitis C virus, Ethanol and Cancer tissues in in-vitro models

Anticancer ACTREC

Homeopathic nosode preparations were tested at ACTREC (Tata, Mumbai), made from cancer-related substances (like HIV nosode, Hepatitis C nosode, Carcinosin, and cancer tissue) on various human cancer cell lines. Many of these potentized preparations significantly slowed the growth of several cancer cell types in vitro, suggesting possible anticancer activity

Conclusions:

  • High-dilution preparations of certain carcinogen-derived nosodes showed measurable anticancer effects in multiple cancer cell lines
  • These findings support further research into their mechanisms and potential applications in cancer biology

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Anticancer ACTREC

Peer-review articles 19

Preparation of Cancer Nosodes from specific cancer tissues

Cancer nosode Pren

This study explains how scientists took specific human cancer tissues (like skin, rectum, stomach, breast, melanoma, thyroid) and characterized the source material and Homeopathic Pharmacopeia of India methods to prepare cancer nosodes. These potentized preparations were documented systematically, improving reliability compared to older, mixed formulations

Conclusions:

  • Cancer nosodes from six distinct human cancer tissues were methodically prepared and standardized for future research or use
  • This systematic approach increases reproducibility and may support further studies on the potential effects of these nosodes

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Cancer nosode Pren

Peer-review articles 20

An experimental in vitro study to evaluate the antimalarial activity of select homeopathy preparations

Antimalaria activity

This in vitro study tested several homeopathic medicines (like China officinalis, Chelidonium, Arsenicum album, and a specially made malaria nosode) to see if they stop malaria parasite activity using a chemical assay that mimics parasite growth. The results showed varying levels of inhibition of heme crystallization, a process important to malaria parasites, suggesting some preparations may affect parasite biology in vitro

Conclusions:

  • Some homeopathic preparations showed measurable inhibition in a lab antimalarial assay
  • These findings support the role of homeopathic medicine in anti-malarial activity

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Antimalaria activity

Peer-review articles 21

Therapeutic potential of HIV nosode 30c as evaluated in A549 lung cancer cells

Anticancer HIV KB (1)

Authors Dr  Anisur Rahman Khuda-Bukhsh and Dr Rajesh Shah, in collaboration with Kalyani university has conducted in vitro study testing a HIV nosode (30c) on human lung cancer cells (A549) and compared effects with normal liver cells. The HIV nosode reduced cancer cell growth and movement, triggered programmed cell death (apoptosis), and affected proteins involved in cell division, while sparing normal cells, suggesting possible anti-cancer properties in vitro

Conclusions:

  • HIV nosode 30c showed anticancer activity by slowing proliferation, reducing migration, and inducing apoptosis in lung cancer cells
  • It modulated key molecular markers (like increased pro-apoptotic proteins and decreased telomerase/Top II) associated with cancer cell death

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Anticancer HIV KB (1)

Peer-review articles 22

A homeopathic nosode, Hepatitis C 30 demonstrates anticancer effect against liver cancer cells in vitro by modulating telomerase and topoisomerase II activities as also by promoting apoptosis via intrinsic mitochondrial pathway

Anticancer Hep C nosode

A newly prepared Hepatitis C nosode (30C) was tested on cancer cells grown in vitro. It reduced the growth of liver cancer cells (HepG2) and triggered signs of programmed cell death (apoptosis) by affecting cancer-linked enzymes and cellular pathways. Normal liver cells were significantly less affected, suggesting a selective anticancer activity of the Hepatitis C nosode in vitro.

Conclusions:

  • Hepatitis C 30C nosode showed anticancer effects in liver cancer cells by inducing apoptosis and altering telomerase/Topoisomerase II enzymes
  • Hep C 30 has demonstrable anticancer effects against liver cancer cells in vitro and potential use in cancer treatment

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Anticancer Hep C nosode

Peer-review articles 23

Preparation, standardization and in vitro safety testing of Mycobacterium nosodes (Emtact- polyvalent nosode)

Preparation, standardization and in vitro safety testing of Mycobacterium nosodes (Emtact- polyvalent nosode)

This study documents systematic preparation and standardized homeopathic Mycobacterium nosode (called Emtact) from multiple strains of Mycobacterium tuberculosis for use in research and clinical settings. Safety and absence of viable bacteria or detectable DNA were established, suggesting the nosodes are safe for oral consumption.

Conclusions:

  • Polyvalent and univalent Mycobacterium nosodes were successfully prepared and standardized following modern scientific techniques
  • In vitro safety tests showed no contamination or detectable DNA at potentized levels, supporting safe use

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Preparation, standardization and in vitro safety testing of Mycobacterium nosodes (Emtact- polyvalent nosode)

Peer-review articles 24

Preclinical evaluation of antiarthritic activity of ultra‑diluted preparations of capsaicin alkaloids (CP‑10), tumor necrosis factor‑alpha, and Magnesium phosphoricum in wistar rats

Preclinical evaluation of antiarthritic activity of ultra‑diluted preparations of capsaicin alkaloids (CP‑10), tumor necrosis factor‑alpha, and Magnesium phosphoricum in wistar rats

This research utilised Wistar rats to test the homeopathic preparations Capsaicin and Magnesium phosphoricum in an experimentally induced arthritis model to determine if they reduce joint swelling and inflammation. Diclofenac was used as a positive control. Magnesium phosphoricum showed a significant reduction in swelling, comparable to the standard anti-inflammatory drug, while other ultra-diluted treatments had less effect.

Conclusions:

  • Magnesium phosphoricum significantly reduced arthritis symptoms in rats
  • Diclofenac and Magnesium phosphoricum showed a significant reduction in the arthritic index on days 7 and 21
  • Ultra-diluted homoeopathic preparation of Magnesium phosphoricum exhibited definite antiarthritic activity.

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Preclinical evaluation of antiarthritic activity of ultra‑diluted preparations of capsaicin alkaloids (CP‑10), tumor necrosis factor‑alpha, and Magnesium phosphoricum in wistar rats

Peer-review articles 25

Potentized, oral preparation of Capsaicin alkaloids and magnesium phosphoricum in treatment of chronic pain: A clinical trial

Potentized, oral preparation of Capsaicin alkaloids and magnesium phosphoricum in treatment of chronic pain: A clinical trial

A double-blind, randomized, comparative study was conducted to evaluate the efficacy and safety of Capsaicin alkaloids and magnesium phosphoricum homeopathy preparations in 116 patients with sub-acute and chronic painful conditions. A statistically significant improvement was reported in terms of reduced pain intensity, decreased stiffness, and decreased joint swelling. Reduction in knee tenderness and a decrease in sleep interference were observed.

 Conclusions:

  • The clinical trial results demonstrated the effectiveness of Capsaicin alkaloids and Magnesium Phosphoricum in reducing pain measured on the Numeric Rating Scale.
  • Ultra-molecular, highly diluted (potentized) Capsaicin alkaloids and Magnesium Phosphoricum were safe and can be used effectively in pain management

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Potentized, oral preparation of Capsaicin alkaloids and magnesium phosphoricum in treatment of chronic pain: A clinical trial

Peer-review articles 26

Effect of Orally Administered Potentized Capsaicin and Dihydrocapsaicin in Humans: A Homeopathic Pathogenetic Trial

Effect of Orally Administered Potentized Capsaicin and Dihydrocapsaicin in Humans: A Homeopathic Pathogenetic Trial

A controlled proving trial of homeopathic preparation of capsaicin and Dihydrocapsaicin was conducted in 22 healthy volunteers. Symptoms were recorded over 5 weeks. Those who took the potentized medicine (verum) reported distinct symptoms similar to those caused by the crude substance, suggesting the preparation had measurable effects compared with a placebo

 Conclusions:

  • The potentized capsaicin/Dihydrocapsaicin produced significant symptom patterns versus placebo in healthy volunteers
  • These findings support the basic homeopathic idea that such potentized substances may trigger characteristic effects and can be used as homeopathic treatment

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Effect of Orally Administered Potentized Capsaicin and Dihydrocapsaicin in Humans: A Homeopathic Pathogenetic Trial

Peer-review articles 27

An In-Vitro Assay Estimating Changes in Melanin Content of Melanoma Cells due to Ultra-Dilute, Potentized Preparations

Melanin assay Hom

This in vitro study evaluated whether highly diluted homeopathic medicines can change the melanin content in murine B16F10 melanoma cells. Researchers treated melanoma cells with homeopathic medicines and measured melanin levels to see if the preparations affected cell behavior compared to untreated controls. The goal was to explore the potential effects of potentialized treatments on pigmentation and determine their biological effects.

 

Conclusions:

  • Some ultra-diluted, potentized preparations altered melanin content in melanoma cells, suggesting a measurable effect in vitro
  • These findings support further research into how potentized homeopathic preparations might influence cell functions and pigmentation pathways

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Melanin assay Hom

Peer-review articles 28

Evaluation of melanogenic and anti-vitiligo activities of homeopathic preparations on murine B16F10 melanoma cells

Anti Vitiligo_Nair

The effect of homeopathy preparations on the production of melanin in melanocytes was determined using B16F10 melanoma cells. Homeopathic preparations Hydroquinone, Arsenicum sulphuratum flavum (ASF), and Phosphorous (30C) showed an increase in melanin content as compared to cell and vehicle controls. A statistically significant increase was seen with Hydroquinone and ASF.

Conclusions:

  • The experiment has revealed an important finding that the small (potentized medicines) dose of the substance stimulates melanogenesis
  • The melanogenesis (pigment formation) approach may be used in vitiligo treatment and therapy
  • The paper highlights emphasises melanogenic pathways and therapeutic implications for pigment restoration

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Anti Vitiligo_Nair

Peer-review articles 29

Hydroquinone: Homoeopathic Pathogenetic Trial

Hydroquinone_HPT

This double-blind, randomized, placebo-controlled trial study involves the administration of potentized hydroquinone in healthy volunteers to see what symptoms it produces. The goal was to derive clear symptom patterns (“proving data”) that could guide clinical use. Volunteers taking the medicine reported distinct symptoms compared to placebo, and no serious safety issues were found

 Conclusions:

  • The Hydroquinone 30 C homeopathic preparation produced qualitatively distinct symptom patterns that could be used for clinical prescribing
  • The trial’s Quantitative and Qualitative Pathogenetic Indices offer a structured way to evaluate proven symptoms

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Hydroquinone_HPT

Peer-review articles 30

A Clinical Evaluation of a Hepatitis C Nosode in the Treatment of Hepatitis C

HCV Clinical trial

This is an open-label study that used a Hepatitis C nosode (30C and 50C) in 24 people with chronic hepatitis C over 24 weeks. Patients were monitored to see if it affected viral load and well-being. On average, viral load dropped by about half by week 12 in many participants, appetite and weight improved, and the nosode was safe.

Conclusions:

  • Responders showed reduced hepatitis C viral load and symptom improvements while taking the nosode
  • The nosode was well tolerated and safe, but results were mixed and suggest that more controlled studies are needed

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HCV Clinical trial

Peer-review articles 31

Hepatitis C Nosode: The preparation and homeopathic pathogenetic trial

Hep-c-nosode-HPT

This double-blind, randomized, placebo-controlled homeopathic drug-proving study evaluated a Hepatitis C nosode (30C, newly prepared by Dr Rajesh Shah) in healthy volunteers. Those taking the nosode reported distinct, quantifiable symptom changes compared to the placebo, generating guiding symptom data for clinical use. Safety was documented, and the method allowed reproducible nosode preparation.

Conclusions:

  • The Hepatitis C nosode produced significantly more symptoms with a pathogenetic effect per volunteer in the verum group 9
  • Verum arm produced more characteristic symptoms than the placebo, supporting homeopathic proving methodology
  • The standardization method provides reproducible preparation and symptom data that may guide clinical prescribing to clinicians in practice

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Hep-c-nosode-HPT

Peer-review articles 32

Clinical trial for evaluation of a Human Immunodeficiency Virus nosode in the treatment for Human Immunodeficiency Virus-Infected individuals

HIV nosode Trial

A newly developed HIV nosode was evaluated in 27 people living with HIV  in an open clinical trial. Viral load, immune cells (CD4), and well-being of participants were monitored for 24 weeks. Some participants showed reduced viral load and increased CD4 counts, better appetite/weight, and no serious side effects, suggesting potential supportive effects of the nosode in this setting

Conclusions:

  • A subset of participants showed reduced viral load and improved immune markers (CD4) after HIV nosode treatment
  • The nosode was well tolerated, with improvements in appetite and weight in many participants.

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HIV nosode Trial

Peer-review articles 33

HIV Nosode The Homeopathic Pathogenetic Trial-Karger

HIV drug proving

This is a randomized, double-blind, placebo-controlled trial of a homeopathic HIV nosode (30C) in healthy volunteers, conducted at Life Force. HIV nosode was administered once weekly for 4 weeks, and symptoms produced were recorded systemically. Those taking the nosode (verum) reported a larger number of distinct symptoms than those taking the placebo, helping create a symptom profile that homeopaths may use when prescribing this remedy. Safety was also monitored.

 Conclusions:

  • The HIV nosode produced distinct symptom patterns vs placebo, useful for homeopathic prescribing.
  • The number of symptoms reported in the verum group was 130, in the placebo group 60. Quantitative pathogenetic index was 0.285 in the verum group, 0.238 in the placebo group; qualitative pathogenetic index was 0.1402 in the verum group as compared to placebo (0.0907).
  • It was well tolerated with no serious adverse effects in this trial.

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HIV drug proving

Peer-review articles 34

Symptom Similarity versus Disease Similarity: Revisiting the Application of the Law of Similars and Challenging the Symptom-Centric Approach in Homeopathy Approach in Homeopathy

Symptom Similarity

This article debates a core concept in homeopathy known as the Law of Similars, which states that a substance that causes symptoms can also help alleviate similar symptoms. The author argues that focusing solely on matching symptoms is insufficient. This fundamental approach needs to be extended beyond the symptoms’ similarity to the disease-pathogenesis similarity when choosing remedies to make treatment more meaningful and effective.

 Conclusions:

  • The paper suggests homeopathy should shift from a symptom-only focus to include disease-cause similarity for better treatment decisions
  • It highlights risks of relying purely on symptoms without understanding pathogenesis, urging a more complete conceptual approach.

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Symptom Similarity

Peer-review articles 35

Need to revamp Tuberculinum and Psorinum nosodes

Revamp nosodes
Revamp nosodes

Peer-review articles 36

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Dr Rajesh Shah, MD (Hom), Global Homeopath

40 Years of Wisdom

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